Notizie
A tutti gli studenti di FARMACIA canale M-Z che seguiranno FISIOLOGIA nell'anno accademico 2023-2024.
Corso di Fisiologia Umana canale M-Z
A.A.2023/2024 inizio delle lezioni martedì 03-10-2023
Lezioni in presenza presso Aula C edificio CU023 (Medicina Legale)
Orario:
martedì 11-13
giovedì 15-17
venerdì 11-13
tutte le informazioni relative al corso sono riportate su elearning
Orari di ricevimento
Per appuntamento
Curriculum
PERSONAL INFORMATION
Working Address: Department of Physiology and Pharmacology “V. Erspamer” Sapienza University of Rome P.le Aldo Moro 5, 00185 Rome, Italy
Telephone: +39 06 49910467; Email myriam.catalano@uniroma1.it; Nationality: Italian
WORK EXPERIENCE
2020- to date: Associate Professor in Physiology, Physiology and Pharmacology Department, Sapienza University of Rome
2012-2020: Researcher in Physiology, Physiology and Pharmacology Department, Sapienza University of Rome.
2008-2011: PostDoc, Physiology and Pharmacology Department, Sapienza University of Rome.
2007-2008: PostDoc, Laboratory for Molecular and Cellular Biology, Medical Research Council, University College of London.
2006-2018: Scientific Collaborator, Istituto Neurologico Mediterraneo NEUROMED, Pozzilli (Isernia)
2003: Fellowship, Pasteur Institute, Rome
EDUCATIONAL AND TRAINING
2007 PhD in Neurophysiology, Sapienza University of Rome
2002 Master’s Degree in Medical Biotechnology, University of Modena
PUBLICATIONS
1. Vilardo L, Cifola I, Nardella M, Pelucchi P, Ciotti MT, Bianchi A, Rinaldi A, Arisi I, Brandi R, d'Onofrio M, Galvanetto N, Gatti G, Catalano M, Lanzuolo C, Guglielmi L, D'Agnano I. Lamin A/C regulates cerebellar granule cell maturation. Cell Biol Toxicol. 2025 Apr 5;41(1):66. doi: 10.1007/s10565-025-10011-z. PMID: 40186700; PMCID: PMC11972193.
2. Garofalo S, Mormino A, Mazzarella L, Cocozza G, Rinaldi A, Di Pietro E, Di Castro MA, De Felice E, Maggi L, Chece G, Andolina D, Ventura R, Ielpo D, Piacentini R, Catalano M, Stefanini L, Limatola C. Platelets tune fear memory in mice. Cell Rep. 2025 Feb 25;44(2):115261. doi: 10.1016/j.celrep.2025.115261. Epub 2025 Feb 3. PMID: 39903668.
3. Rosito M, Maqbool J, Reccagni A, Mangano M, D'Andrea T, Rinaldi A, Peruzzi G, Silvestri B, Rosa A, Trettel F, D'Alessandro G, Catalano M, Fucile S, Limatola C. Ketogenic diet induces an inflammatory reactive astrocytes phenotype reducing glioma growth. Cell Mol Life Sci. 2025 Feb 8;82(1):73. doi: 10.1007/s00018-025-05600-4. PMID: 39921723; PMCID: PMC11807044.
4. Rinaldi A, Balietti M, Principi E, De Luca M, De Felice E, Narcisi FM, Vilardo L, Rosito M, Piacentini R, D'Alessandro G, D'Agnano I, Maggi L, Conti F, Limatola C, Catalano M. BV2-derived extracellular vesicles modulate microglia inflammatory profile, neuronal plasticity, and behavioural performances in late adult mice. Brain Behav Immun. 2024 Nov;122:58-74. doi: 10.1016/j.bbi.2024.08.012. Epub 2024 Aug 10. PMID: 39128568.
5. Catalano M, Limatola C, Trettel F. Non-neoplastic astrocytes: key players for brain tumor progression. Front Cell Neurosci. 2024 Jan 16;17:1352130. doi: 10.3389/fncel.2023.1352130. PMID: 38293652; PMCID: PMC10825036.
6. Familiari P, Relucenti M, Lapolla P, Palmieri M, Antonelli M, Cristiano L, Barbaranelli C, Catalano M, D'Angelo L, Familiari G, Santoro A, Frati A, Bruzzaniti P. Adult IDH Wild-Type Glioblastoma Ultrastructural Investigation Suggests a Possible Correlation between Morphological Biomarkers and Ki-67 Index. Biomedicines. 2023 Jul 12;11(7):1968. doi: 10.3390/biomedicines11071968.
7. Di Palma M*, Catalano M*, Serpe C, De Luca M, Monaco L, Kunzelmann K, Limatola C, Conti F, Fattorini G. Lipopolysaccharide augments microglial GABA uptake by increasing GABA transporter-1 trafficking and bestrophin-1 expression. Glia. 2023 Nov;71(11):2527-2540. doi: 10.1002/glia.24437. Epub 2023 Jul 10. PMID: 37431178.
8. Serpe C, Michelucci A, Monaco L, Rinaldi A, De Luca M, Familiari P, Relucenti M, Di Pietro E, Di Castro MA, D'Agnano I, Catacuzzeno L, Limatola C, Catalano M. Astrocytes-Derived Small Extracellular Vesicles Hinder Glioma Growth. Biomedicines. 2022 Nov 17;10(11):2952. doi: 10.3390/biomedicines10112952. PMID: 36428520; PMCID: PMC9688032.
9. Catalano M. Editorial: Brain Tumors and Neuroinflammation. Front Cell Neurosci. 2022 Jun 1;16:941263. doi: 10.3389/fncel.2022.941263. eCollection 2022.
10. Morotti M, Gaeta A, Limatola C, Catalano M, Di Castro MA, Grassi F. Early Developmental Changes of Muscle Acetylcholine Receptors Are Little Influenced by Dystrophin Absence in mdx Mouse. Life (Basel). 2022 Nov 12;12(11):1861. doi: 10.3390/life12111861. PMID: 36430996; PMCID: PMC9696329.
11. Catalano, M., Serpe, C., Limatola, C. Microglial Extracellular Vesicles as Modulators of Brain Microenvironment in Glioma. International Journal of Molecular Sciences, 2022, 23(21), 13165.
12. Morotti M, Garofalo S, Cocozza G, Antonangeli F, Bianconi V, Mozzetta C, De Stefano ME, Capitani R, Wulff H, Limatola C, Catalano M, Grassi F. Muscle Damage in Dystrophic mdx Mice Is Influenced by the Activity of Ca2+-Activated KCa3.1 Channels. Life (Basel). 2022 Apr 5;12(4):538. doi: 10.3390/life12040538. PMID: 35455028; PMCID: PMC9025295.
13. Serpe C, Monaco L, Relucenti M, Iovino L, Familiari P, Scavizzi F, Raspa M, Familiari G, Civiero L, D'Agnano I, Limatola C, Catalano M. Microglia-Derived Small Extracellular Vesicles Reduce Glioma Growth by Modifying Tumor Cell Metabolism and Enhancing Glutamate Clearance through miR-124. Cells. 2021 Aug 12;10(8):2066. doi: 10.3390/cells10082066. PMID: 34440835; PMCID: PMC8393731.
14. Nalli M, Armijos Rivera JI, Masci D, Coluccia A, Badia R, Riveira-Muñoz E, Brambilla A, Cinquina E, Turriziani O, Falasca F, Catalano M, Limatola C, Esté JA, Maga G, Silvestri R, Crespan E, La Regina G. New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains. Eur J Med Chem. 2020; 208:112696. doi:10.1016/j.ejmech.2020.112696.
15. Catalano M, D'Alessandro G, Trettel F, Limatola C. Role of Infiltrating Microglia/Macrophages in Glioma. Adv Exp Med Biol. 2020;1202:281–298. doi:10.1007/978-3-030-30651-9_14
16. Fattorini G*, Catalano M*, Melone M, Serpe C, Bassi S, Limatola C, Conti F. Microglial expression of GAT-1 in the cerebral cortex. (2019) Glia. doi: 10.1002/glia.23745.
17. Grimaldi A, Serpe C, Chece G, Nigro V, Sarra A, Ruzicka B, Relucenti M, Familiari G, Ruocco G, Pascucci GR, Guerrieri F, Limatola C, Catalano M. Microglia-Derived Microvesicles Affect Microglia Phenotype in Glioma. (2019). Front Cell Neurosci. doi: 10.3389/fncel.2019.00041.
18. Colella B, Faienza F, Carinci M, D'Alessandro G, Catalano M, Santoro A, Cecconi F, Limatola C, Di Bartolomeo S. Autophagy induction impairs Wnt/β-catenin signalling through β-catenin relocalisation in glioblastoma cells.(2019) Cell Signal 52 (357-364).
19. Grimaldi A, D’Alessandro G, Di Castro M A, Lauro C, Singh V, Pagani F, Sforna L, Grassi F, Di Angelantonio S, Catacuzzeno L, Wulff H, Limatola C & Catalano M Kv1.3 activity perturbs the homeostatic properties of astrocytes in glioma (2018) Sci. Rep.8:7654
20. D’Alessandro G, Limatola C, Catalano M. Functional roles of the Ca2+-activated K+ channel, KCa3.1, in brain tumors. (2017) Curr Neuropharmacol. (IF 3)
21. Famiglini V, La Regina G, Coluccia A, Masci D, Brancale A, Badia R, Riveira-Muñoz E, Esté JA, Crespan E, Brambilla A, Maga G, Catalano M, Limatola C, Formica FR, Cirilli R, Novellino E, Silvestri R. Chiral Indolylarylsulfone Non-Nucleoside Reverse Transcriptase Inhibitors as New Potent and Broad Spectrum Anti-HIV-1 Agents. (2017). J Med Chem.
22. Cellot G, Maggi L, Di Castro MA, Catalano M, Migliore R, Migliore M, Scattoni ML, Calamandrei G, Cherubini E. Premature changes in neuronal excitability account for hippocampal network impairment and autistic-like behavior in neonatal BTBR T+tf/J mice. (2017) Sci Rep. 7:39726.
23. D'Alessandro G, Grimaldi A, Chece G, Porzia A, Esposito V, Santoro A, Salvati M, Mainiero F, Ragozzino D, Di Angelantonio S, Wulff H, Catalano M, Limatola C. KCa3.1 channel inhibition sensitizes malignant gliomas to temozolomide treatment (2016) Oncotarget, DOI: 10.18632/oncotarget.8761
24. Grimaldi A, D'Alessandro G, Golia MT, Grössinger EM, Di Angelantonio S, Ragozzino D, Santoro A, Esposito V, Wulff H, Catalano M* and Limatola* C. KCa3.1 inhibition switches the phenotype of glioma-infiltrating microglia/macrophages (2016) Cell Death and Disease, 7, e2174.
25. Sciaccaluga, M., Moriconi, C., Martinello, K., Catalano, M., Bermudez, I., Stitzel, J.A., Maskos, U., Fucile, S. Crucial role of nicotinic α5 subunit variants for Ca2+ fluxes in ventral midbrain neurons (2015) FASEB Journal, 29 (8), pp. 3389-3398. (IF 5, CI 6)
26. Catalano, M., D'Alessandro, G., Lepore, F., Corazzari, M., Caldarola, S., Valacca, C., Faienza, F., Esposito, V., Limatola, C., Cecconi, F., Di Bartolomeo, S. Autophagy induction impairs migration and invasion by reversing EMT in glioblastoma cells (2015) Molecular Oncology
27. Pagani F, Paolicelli R, Murana E, Cortese B, Di Angelantonio S, Zurolo E, Guiducci E, Ferreira T.A, Garofalo S, Catalano M, D’Alessandro G, Porzia A, Peruzzi G, Mainiero F, Limatola C Gross C and Ragozzino D. (2015). Defective microglial development in the hippocampus of Cx3cr1 deficient mice. Front. Cell. Neurosci. 9:111
28. Lauro C, Catalano M, Trettel F, Limatola C. (2015) Fractalkine in the nervous system: Neuroprotective or neurotoxic molecule? Annals of the New York Academy of Sciences 1351 (1).)
29. Lauro C., Catalano M., Di Paolo E., Chege G., de Costanzo I., Trettel F., Limatola C (2015) Fractalkine/CX3CL1 engages different neuroprotective responses upon selective glutamate receptor overactivation. Front Cell. Neurosci. 8:472
30. Rosito M, Lauro C, Chece G, Porzia A, Monaco L, Mainiero F, Catalano M, Limatola C, Trettel F (2014) Trasmembrane chemokines CX3CL1 and CXCL16 drive interplay between neurons, microglia and astrocytes to counteract pMCAO and excitotoxic neuronal death.Front Cell Neurosci.8:193
31. Deflorio C, Catalano M, Fucile S, Limatola C, Grassi F. (2014) Fluoxetine prevents acetylcholine-induced excitotoxicity blocking human endplate acetylcholine receptor. Muscle Nerve 49(1):90-7.
32. Roseti C, Fucile S, Lauro C, Martinello K, Bertollini C, Esposito V, Mascia A, Catalano M, Aronica E, Limatola C, Palma E. (2013) Fractalkine/CX3CL1 modulates GABAA currents in human temporal lobe epilepsy. Epilepsia 54(10):1834-44
33. D'Alessandro G*, Catalano M*, Sciaccaluga M, Chece G, Cipriani R, Rosito M, Grimaldi A, Lauro C, Cantore G, Santoro A, Fioretti B, Franciolini F, Wulff H, Limatola C. (2013) KCa3.1 channels are involved in the infiltrative behavior of glioblastoma in vivo. Cell Death Dis. 4:e773.
34. Catalano M*, Lauro C*, Cipriani R, Chece G, Ponzetta A, Silvia DA, Ragozzino D, Limatola C. (2013) CX3CL1 protects neurons against excitotoxicity enhancing GLT-1 activity on astrocytes. J Neuroimmunol. 263(1-2):75-82
35. Bertollini C., Murana E., Mosca L., D'Erme M., Scala F., Francioso A., Catalano M., Limatola C., Bregestovski P., Di Angelantonio S., Ragozzino D. (2012). Transient increase in neuronal chloride concentration by neuroactive amino acids released from glioma cells. Front. Mol. Neurosci, 5:100
36. Deflorio C, Palma E, Conti L, Roseti C, Manteca A, Giacomelli E, Catalano M, Limatola C, Inghilleri M, Grassi F. (2012): Riluzole blocks human muscle acetylcholine receptors. J Physiol. 590(Pt 10):2519-28
37. Lauro C., Cipriani R., Catalano M., Trettel F., Chece G., Brusadin V., Antonilli L., van Roijen N., Eusebi F., Fredholm B.B., Limatola C. (2010): Adenosine A(1) Receptors and Microglial Cells Mediate CX3CL1-Induced Protection of Hippocampal Neurons Against Glu-Induced Death. Neuropsychopharmacology. 35(7):1550-9
38. Sciaccaluga M., Fioretti B., Catacuzzeno L., Pagani F., Bertollini C., Rosito M., Catalano M., D'Alessandro G., Santoro A., Cantore G., Ragozzino D., Castigli E., Franciolini F., Limatola C. (2010): CXCL12-induced glioblastoma cell migration requires intermediate conductance Ca2+-activated K+ channel activity. Am J Physiol Cell Physiol 299(1):C175-84
39. Catalano M. *, Trettel F. *, Cipriani R., Lauro C., Sobrero F., Eusebi F., Limatola C. (2008): Chemokine CXCL8 modulates GluR1 phosphorylation J. Neuroimmunol. 198(1-2):75-81.
40. Cingolani L.A., Thalhammer A., Yu L.M.Y., Catalano M., Ramos T., Colicos M.A., Goda Y. (2008) Activity-dependent regulation of synaptic AMPA receptor composition and abundance by beta3 integrins Neuron 58(5):749-762.
41. Limatola C., Massa V., Lauro C., Catalano M., Giovanetti A., Nuccitelli S., Spinedi A. (2007) Evidence for a role of glycosphingolipids in CXCR4-dependent cell migration. FEBS Letters 581(14):2641-6.
42. Lauro C. *, Catalano M. *, Trettel F., Mainiero F., Ciotti M. T., Eusebi F., Limatola C. (2006) The Chemokine CX3CL1 Reduces Migration and Increases Adhesion of Neurons with Mechanisms Dependent on the β1 Integrin Subunit. J Immunol. 177(11):7599-606.
43. Pagani F., Lauro C., Fucile S., Catalano M., Limatola C., Eusebi F., Grassi F. (2006) Functional properties of neurons derived from fetal mouse neurospheres are compatible with those of neuronal precursors in vivo. J. Neurosci. Res. 83(8):1494-1501.
44. Limatola C., Lauro C., Catalano M., Di Angelantonio S., Bertollini C., Ragozzino D., and Eusebi F. (2005) Chemokine fractalkine/CX3CL1 reduces glutamate-mediated excitotoxic death of cultured hippocampal neurons. J Neuroimmunol. 166(1-2):19-28.
45. Limatola C., Di Bartolomeo S., Catalano M., Trettel F., Fucile S., Castellani L., Eusebi F. (2005) Cys residues are critical for chemokine receptor CXCR2 functional properties Exp Cell Res. 307(1):65-75.
46. Trettel F., Di Bartolomeo S., Lauro C., Catalano M., Ciotti M.T., Limatola C. (2003) Ligand independent CXCR2 dimerization. J. Biol. Chem. 278(42):40980-8.