DONATELLA PONTI

Il corso di Patologia Generale e Molecolare con Terminologia Medica avrà inizio giovedì 1 Ottobre 2024 orario 11:00-14:00 - Facoltà di Farmacia e Medicina, Corso della Repubblica 79, Latina. 

Il corso si svolgerà nei seguenti giorni e orari:

Martedì 11:00-14:00

Giovedì 11:00-14:00

Il corso di Oncologia Molecolare avrà inizio lunedì 7 Ottobre presso l'Aula C Edificio CU023 Medicina Legale. Facoltà di Farmacia e Medicina, Piazzale Aldo Moro 6, Roma.

Il corso si svolgerà nei seguenti giorni e orari:

Lunedì 8:30-11:00

Mercoledì 9:00-11:00

Il corso di Oncologia Molecolare dal 18 ottobre 2024 seguirà i seguenti giorni e orari:

Lunedì 8:30-11:00 Aula C Edificio CU023 Facoltà di Farmacia e Medicina

Venerdì 8:00-10:00 Aula C Edificio CU018 Facoltà di Farmacia e Medicina

PERSONAL INFORMATION

DONATELLA PONTI

Department of Medical-Surgical Sciences and Biotechnologies, University of Rome “Sapienza”, Corso Della Repubblica 79 Latina 04100 Italy
Email: donatella.ponti@uniroma1.it;
Sex: F | Nationality: Italian
Native Language: Italian, Second Language: English
CURRENT POSITION - Researcher (RU); SSD MEDS-02/A (MED04) GENERAL PATHOLOGY
University of Rome La Sapienza Department of Medical-Surgical Sciences and Biotechnologies, University of Rome.
- President of Course in Childhood Neuro and Psychomotricity Medical Faculty University of Rome La Sapienza Department of Medical-Surgical Sciences and Biotechnologies, University of Rome Latina.
- Responsible Course in Molecular Oncology CTF (MED/04) Department of Chemistry and Technology of Drugs Medical Faculty University of Rome
- Responsible Course in Molecular Phatology CTF (MED04) Department of Chemistry and Technology of Drugs Medical Faculty University Latina.
RESEARCH TOPICS / EXPERIENCES - Molecular mechanisms of disease
- Nuclear and nucleolar trafficking
- Protein expression/DNA manipulation
- Biological system: cell lines and mouse model
SCIENTIFIC / TECHNICAL QUALIFICATION
(Scopus) H-index:
Total IF
Average impact factor 15
145,39
4,7
Publications:
Patent
Book 31
2
1
Citations: 583
THEMATIC AREA KEYWORDS Biopharma & health: Biotechnology, Molecular Biology, Biochemistry, Cell Pathology; nucleolar metabolism, immunometabolism, ribosome biogenesis, peptide, and protein expression.

EDUCATION AND TRAINING

June 2020 Diploma Animal Laboratory Course B (FELASA B) Animal Laboratory Science. KU Leuven University, Leuven Belgium
September 2012 EMBO Career activity: How to get your paper published. Nice France
March 2015 Mouse Genetics; Models for Human Disease ICGBE Trieste Italy
since 2009 Enrolled on the Register of Biologists (ONB) n. EA_018906

1998 to 2001 PhD in Biochemistry. University La Sapienza di Roma, Piazzale Aldo Moro 5, 00185 Rome. Dept. of Biochemistry. Supervisor. Prof. D. Barra
March 1997
School in Biotechnology (summa cum laude)
University’ of Rome La Sapienza, Dept. of Biochemistry Supervisor: Prof. F. Bossa

1991 Biological Sciences Degree (summa cum laude) University “La Sapienza” Rome. University of Rome Sapienza and Division Biotechnologies Italian National Agency for New Technologies, Energy and Sustainable Economic Development ENEA. Prof. Giovanni Giuliano.

WORK EXPERIENCE

Sept. 2019 to Dec 2021

Visiting Scientist
Visiting in the Prof. M. Mazzone laboratory. Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology (CCB), VIB, Leuven, Belgium. KU Leuven University, Campus Gasthuisberg ON4 Herestraat 49, 3000 Leuven, Belgium.
https://vib.be

May 2017 to August 2017

Guest Scientist
Guest Scientist in the Prof. J. Kirsh laboratory, Heidelberg University, Medical Faculty Department of Medical Cell Biology Institute for Anatomy and Cell Biology INF 307, 69120 Heidelberg Germany Supported by funding of the German Academic Exchange Service (DAAD fellow personal. No 91609354 section ST24) Funding programme/-ID Research stays for University Academics and Scientists, 2017 (57314018).
http://www.ana.uni-heidelberg.de/

June 2017 to August 2017 Guest Visiting
Guest Scientist in Prof. Lyko F. laboratory Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany. German Cancer Research Center (DKFZ). https://www.dkfz.de

since Dec 2010 Researcher (SSD MEDS/02A) with permanent position. Department of Medical-surgical Science and Biotechnologies, University of Rome La Sapienza, Medical Faculty, Corso della Repubblica 79, Latina 04100 Italy.

April 2010 to Dec 2010 Post-doc position (Fellow) Laboratory of Molecular Oncology. Supervisor Prof.ssa A. Calogero. Department of Experimental Medicine and Pathology University of Rome, Corso della Repubblica 79, 04100 Latina, Italy University Sapienza.
2008 to 2009 Math and Science Teacher Secondary School, via B. Lesen 2, Campagnano, Rome Italy.
2005 to 2007 Post-doc position (Cenci Bolognetti fellowship)
Department of Biotechnology and Hematology. Supervisor F. Gigliani. University of Rome, Piazzale Aldo Moro 5 00185 Roma Italy.
2002 to 2004 Research assistant Department of Biotechnology and Hematology. Supervisor F. Gigliani. University of Rome, La Sapienza Piazzale Aldo Moro 5 00185 Roma Italy
2001 to 2002 Post-doc fellow. Department of Biochemistry. Supervisor Prof.ssa Donatella Barra. University of Rome, La Sapienza Piazzale Aldo Moro 5, 00185 Rome Italy.
1998 to 2001 PhD fellowship. Department of Biochemistry. Supervisor Prof.ssa Donatella Barra. University of Rome, La Sapienza Piazzale Aldo Moro 5, 00185 Rome Italy.
1997 to 1998 Fellowship supported by Cenci Bolognetti Foundation. Department of Biochemistry. Supervisor Prof.ssa Donatella Barra. University of Rome, La Sapienza Piazzale Aldo Moro 5, 00185 Rome.
1995 to 1996 CNR fellowship, Department of Biochemistry. Supervisor Prof.ssa Donatella Barra. University of Rome, La Sapienza Piazzale Aldo Moro 5, 00185 Rome.
1991 to 1995 CNR Fellowship. Department of Biotechnology. Supervisor Prof. Giovanni Giuliano
Italian National Agency for New Technologies, Energy and Sustainable Economic Development ENEA/INN-BIO-AG via Anguillarese Rome Italy.

MAIN ROLES AND RESPONSIBILITIES

Since February 2025
Member of Animal Welfare Body (OPBA) Department of Medical-Surgical Science and Biotechnology, University of Rome Sapienza, Latina.

Since March 2024

Member of “Giunta di Facoltà” Faculty of Pharmacy and Medicine University of Rome Sapienza (2024/2026).

2025
Thesis Supervisor: student Federico Forzati, Degree in Biomedical Laboratory Techniques. Department of Medical-Surgical Science and Biotechnology, University of Rome Sapienza, Latina.

2025
Thesis Supervisor: student Aurora Mosetti, Degree in CTF. Department of Medical-Surgical Science and Biotechnology, University of Rome Sapienza, Latina.
Since 01.11.2023 President of the Course in Childhood Neuro and Psychomotricity Medical Faculty University of Rome La Sapienza Priverno ASL Latina.
Since 2023 Responsible of the Course Molecular Oncology (CTF) (MED04) code n.1023433
Department of Chemistry and Technology of Drugs Medical Faculty University of Rome 8CFU (64h)
2013 to 2019

Coordinator: Course “Molecular and Cellular Basis of the Life” Code n. 1034944 (BIO13/MED03/FIS07/BIO10) Cds 16007- Cds 29864– Medical Faculty, University of Rome La Sapienza. Latina 04100 Italy.
Since 2022 Coordinator: Course “Molecular Basis of the Life” Code n. 1034829 BIO13/MED03/BIO10/FIS07) Cds 29875– Medical Faculty, University of Rome La Sapienza. Priverno. 04100 Italy.
March 2023 Graduate commission member Course Cod. n. 16011 Faculty of Medicine, University Sapienza. Polo Pontino. Via dei Cappucini. Gaeta (LT).
Since 2022 Coordinator: Course Molecular and General Pathology with Medical Terminology cod. n. 1038200 (CTF) (MED04) –Department of Chemistry and Technology of Drugs Medical Faculty, University of Rome La Sapienza. Latina 04100 Italy.
2018 Graduate commission member Course Cod. n. 16011 Faculty of Medicine, University Sapienza. Polo Pontino. Via dei Cappucini. Gaeta (LT).
2018 Graduate commission member Course Cod. n. 16011 Faculty of Medicine, University Sapienza. Polo Pontino. Via dei Cappuccini. Gaeta (LT).
Since 2012 Supervisor of the Instrumental Laboratory floor 1 at the Department of Medical-Surgical Science and Biotechnologies, University La Sapienza, Faculty of Medicine, Corso della Repubblica 79, Latina 04100 Italy.
2014 to 2017 Technical Supervisor of the animal laboratory (Charles River) at the Department of Medical-surgical Science and Biotechnologies, University of Rome La Sapienza, Faculty of Medicine, Corso della Repubblica 79, Latina 04100 Italy.
2012 PI project: transgenic mouse model Egr1 -/-. (Research project Dlg 116/92. Dlg n.66/2011-A, Ministry of Health).
2022/2023 Thesis Supervisor: student Selenia di Rosa. Degree in in Biomedical Laboratory Techniques. Department of Medical-Surgical Science and Biotechnology University Sapienza, Latina.
2018 to 2020 Thesis Supervisor: student Marzia Tagliaferro Degree in Biotechnology. Department of Medical-Surgical Science and Biotechnology, University of Rome Sapienza, Latina (2018/2020)
06/09/2022
28/05/2024 President Commission for the admission to Single Cycle Degree (Six Years) Faculty Pharmacy and Medicine, Medicine and Dentistry, Medicine and Psychology. Latina.
15/09/2022 President Commission for the admission to the Courses for Health Care Profession Faculty Pharmacy and Medicine. Latina.
2016-2017 Thesis Supervisor: student Marzia Tagliaferro. Degree in in Biomedical Laboratory Techniques. Department of Medical-Surgical Science and Biotechnology University Sapienza, Latina.
2015 Thesis Supervisor of the student Luca Soscia. Degree in Tecniche di laboratorio Biomedico. Department Medical-surgical Science and Biotechnology, University Sapienza Latina
2007
Thesis Supervisor: student Maria Troiano. PhD in Human Biology and Genetics Department of Biotechnology and Hematology, University of Rome La Sapienza.

SERVICE TO NATIONAL AND INTERNATIONAL COMMUNITY

2020
Member of the DAAD Italian Commission (preselection DAAD PROJECT) Servizio tedesco per lo scambio accademico c/o Sapienza Università di Roma - Via del Castro Laurenziano, 9 00161 Roma.

Since 2012

Member Reviewer Cineca MIUR

TEACHING EXPERIENCE

ù
Since 2024/2025
Assistant Professor in Molecular and General Pathology and Immunology (MED04) in english CTF Polo Pontino (3CFU) Department of Chemistry and Technology of Drugs University of Rome Sapienza Polo Pontino

since 2022
Assistant Professor in Molecular and General Pathology and Immunology (MED04) in english CTF Polo Pontino (3CFU) Department of Chemistry and Technology of Drugs University of Rome Sapienza Polo Pontino

Assistant Professor in Molecular and General Pathology with Medical Terminology (MED04) code n. 1038200 Polo Pontino (3CFU) Department of Chemistry and Technology of Drugs University of Rome Sapienza Polo Pontino
since 2022 Coordinator of the Course Molecular and General Pathology with Medical Terminology (MED04) Department of Chemistry and Technology of Drugs University of Rome Sapienza Polo Pontino
since 2022 Coordinator Course “Molecular Basis of the Life” (MED03) Code n. 1034829 course n. 29875 “Molecular Basis of the life” University of Rome Sapienza Polo Pontino Priverno.
since 2022 code 29875 Genetics (MED03) (1CFU) Course “Molecular Basis of the Life” code n.1034829-Faculty of Medicine, University of Rome Sapienza Polo Pontino. Priverno.
since 2022 ADE code n. AAF1433 (1CFU) Course n. 29881. Faculty of Medicine, University of Rome Sapienza Polo Pontino
since 2022 Medical Statistics (MED01) code n. 10335043 (1CFU) Course 29881 University of Rome Sapienza Polo Pontino
since 2021 Biology (BIO13). (1CFU) Course Cod. 1034944 -Faculty of Medicine, University of Rome Sapienza Polo Pontino.
since 2021
Genetics (MED03). (1CFU) Course Cod. 1035043
Faculty of Medicine, University of Rome La Sapienza. Polo Pontino.
since 2021

Pathology (MED04) (2CFU) course Cod.16011 Faculty of Medicine, University Sapienza. Polo Pontino. Gaeta
2013 to 2019 Biology (BIO13) and Genetics (MED03) from 2013 to 2014 (36h/year) and Biology (BIO13) from 2015 to 2019 (24h/year), course Cod. 1034944
Faculty of Medicine, University Sapienza.
2013 to 2019 Coordinator of the Course “Molecular and Cellular Basis of the Life” (BIO13/MED03/FIS07/BIO10) course Cod. 1034944 – Medical Faculty, University of Rome La Sapienza. Latina 04100 Italy.
2014-2019 Pathology and Physiopathology (MED04) (2 CFU) (24h/year) cod. 16011.
Faculty of Medicine, University of Rome La Sapienza.
2012-2019 Biology (BIO13) (3CFU) course cod.1035043-Faculty of Medicine, University of Rome La Sapienza.
2012-2019 Genetics (MED03) (3CFU) course cod.1035043-Faculty of Medicine, University of Rome La Sapienza.
2011-2013 Pathology (MED04) 2CFU course cod16011 course W -Faculty of Medicine, University of Rome La Sapienza.
2011-2014 Pathology Anatomy course cod. 16011 Course W (1CFU) cod. 1034951 (MED08) Faculty of Medicine, University of Rome La Sapienza.

RESEARCH PROJECT OR RESEARCH COLLABORATION

2024 Principal Investigator, Academic Funding SAPIENZA FIBRILLARIN AND THE NUCLEOLUS IN HUMAN MACROPHAGE POLARIZATION Protocol N. RM124190FE03911C

2023 New molecular mechanisms underlying BRAFi/MEKi-induced cardiotoxicity: a multidisciplinary research project from bench to bedside. Progetti Dipartimentali PI. SCIARRETTA Sebastiano N. RD12318AAABE3A08 (Component).
2022 Principal Investigator, Academic Funding NUCLEOLAR ErbB3: A NEW TARGET IN GLIOBLASTOMA - Protocol N.RP1221816BAC3D73

2022 Funding for researcher provided by “Region Lazio” (Personal funding)
2020 Academic funding Sapienza 2020 (Principal Investigator)
RM11916B410542D4
2019 Academic funding Sapienza 2019 Individual funding (Principal Investigator)
Individual funding 2018 ErbB3 AND NUCLEOLAR METABOLISM - n. protocol RP11816433CD0FDC.
2017 Individual funding for research activity 2017 MIUR (FFARB) C.U.P. B25D17000260005
2017 Grant DAAD scholarship: Personal ref. no.: 91609354. Funding programme/-ID: Research Stays for University Academics and Scientists, 2017 (57314018). Deutscher Akademischer Austauschdienst German Academic Exchange service. Start of funding 01/05/17; End funding 31/07/17; Destination country: Germany Institution: Universität Heidelberg.
2017 Academic funding 2017 Sapienza “Role of the translation factor eIF6 in ribosome biogenesis and differential translation of specific mRNAs “(Participant)
2016 Academic Funding 2016 Sapienza “ErbB3: a new player of nucleolar metabolism” (Principal investigator) RP116155037D13E1
2015 Academic Funding 2015 Sapienza “Crosstalk between B23/ARF/EGR1 nucleolar network and ErbB3 receptor in glioma cells” code number C26A15HF29 (Principal investigator).
2014 Academic Funding 2014 Sapienza - Prot. n. 0067282 del 20.11.2014. “EGR1/ARF/B23 nucleolar network in glioma cells” code number C26A14WBCS (Principal investigator).
2013 Academic Funding 2013 Sapienza code number C26A139S3N “Can Egr1 influence growth by controlling ribosomal metabolism?” (Principal Investigator)
2012 Academic Funding 2012 Sapienza code number C26A12T3C4 “Glioma stem Cells and KCa3.1 channel” (Principal Investigator)
2011 Collaboration with the Prof. A. Gelman laboratory, Department of Surgery Washington University School of Medicine CB8109 4590 Children’s Place, Suite 9600 St. Louis, MO 63110 (314) 362-4533.
2011 Academic Funding 2011 Sapienza code number C26A11TAF “Role of nucleolar compartment in gliomas” (Principal Investigator)
2011 PRIN 2011 funding MIUR (Programmi di Ricerca di Interesse Nazionale) Prot. 2010 ZESJWN_007 (Principal Investigator).

HONOURS, AWARDS, MEMBERSHIPS, OTHER QUALIFICATIONS

Member
2020 DAAD Italian Commission (preselection DAAD fellowship)

2017 Winer Fellowship supported by DAAD (Deutscher Akademischer Austauschdienst e.V., Kennedyallee, 53175 Bonn) 2017 at Heidelberg University Germany.
2017-2019 Ethics committee of Department of Medical-Surgical Sciences and Biotechnology
2015-2019 Italian Association of the book
2012 Member of National Reviewer CINECA, MIUR
Since 2009 National Register of Biologist
1997 Award thesis in Biotechnology- University of Study of Rome Sapienza

PUBLICATIONS

Contribution
Article Year IF

Ponti, D. The Nucleolus: A Central Hub for Ribosome Biogenesis and Cellular Regulatory Signals. Int. J. Mol. Sci. 2025, 26, 4174. https://doi.org/10.3390/ijms26094174 2025 4.9

Second author

Davide Barbagallo, Donatella Ponti, Barbara Bassani, Antonino
Bruno, Laura Pulze, Shreya A. Akkihal, Jonahunnatha N. George-William, Rohit
Gundamaraju, Paola Campomenosi. MiR-223-3p in cancer development and cancer drug resistance: same coin, different faces (accepted in International Journal of Molecular Sciences July 23, 2024) 2024 5.6

Scolaro T, Manco M, Pecqueux M, Amorim R, Trotta R, Van Acker HH, Van Haele M, Shirgaonkar N, Naulaerts S, Daniluk J, Prenen F, Varamo C, Ponti D, Doglioni G, Ferreira Campos AM, Fernandez Garcia J, Radenkovic S, Rouhi P, Beatovic A, Wang L, Wang Y, Tzoumpa A, Antoranz A, Sargsian A, Di Matteo M, Berardi E, Goveia J, Ghesquière B, Roskams T, Soenen S, Voets T, Manshian B, Fendt SM, Carmeliet P, Garg AD, DasGupta R, Topal B, Mazzone M. Nucleotide metabolism in cancer cells fuels a UDP-driven macrophage cross-talk, promoting immunosuppression and immunotherapy resistance. Nat Cancer. 2024 Jun 6. doi: 10.1038/s43018-024-00771-8. Epub ahead of print. PMID: 38844817. 2024
22,7

Last author and corresponding author Tagliaferro and Donatella Ponti. The Signaling of Neuregulin-Epidermal Growth Factor Receptors and Its Impact on the Nervous System. Neuroglia 2023, 4(4), 253-274; doi.org/10.3390/neuroglia4040018. A special issue of Neuroglia (ISSN 2571-6980). Special Issue "Glioblastoma (GBM) Brain Tumor Invasion and Consequences on Diagnosis, Clinical Strategies and Therapy" 2023 3.3
Pulcrano S, De Gregorio R, De Sanctis C, Lahti L, Perrone-Capano C, Ponti D, di Porzio U, Perlmann T, Caiazzo M, Volpicelli F, Bellenchi GC. Lmx1a-Dependent Activation of miR-204/211 Controls the Timing of Nurr1-Mediated Dopaminergic Differentiation. Int J Mol Sci. 23:6961. doi:10.3390/ijms23136961
2022
6.2
Last author and
Corresponding author Tagliaferro M, Rosa P, Bellenchi GC, Bastianelli D, Trotta R, Tito C, Fazi F, Calogero A, Ponti D. Nucleolar localization of the ErbB3 receptor as a new target in glioblastoma. BMC Mol Cell Biol. 2022 ;23(1):13. doi: 10.1186/s12860-022-00411-y 2022 2.8
Sönmez A, Mustafa R, Ryll ST, Tuorto F, Wacheul L, Ponti D, Litke C, Hering T, Kojer K, Koch J, Pitzer C, Kirsch J, Neueder A, Kreiner G, Lafontaine DLJ, Orth M, Liss B, Parlato R. Nucleolar stress controls mutant Huntington toxicity and monitors Huntington's disease progression. Cell Death Dis. 2021;12(12):1139. doi: 10.1038/s41419-021-04432-x
2021 8.4
Manuel Ehling, Ward Celus, Rosa Martín-Pérez, Roser Alba-Rovira, Sander Willox, Donatella Ponti, Maria Cinta Cid, Elizabeth A. V. Jones, Giusy Di Conza, Massimiliano Mazzone (2020) B55a/PP2A limits endothelial cell apoptosis during vascular remodeling: a complementary approach to kill pathological vessels? Circ Res. Aug 28;127(6):707-723. doi: 10.1161/CIRCRESAHA.119.316071. 2020 17.3
Mohsen Ibrahim, Davide Scozzi, Kelsey A Toth, Donatella Ponti, Daniel Kreisel, Cecilia Menna, Elena De Falco, Antonio D’Andrilli, Erino A. Rendina, Antonella Calogero, Alexander S. Krupnick, and Andrew E. Gelman. Naïve CD4+ T cells carrying a TLR2 agonist overcome TGFbeta-mediated tumor immune evasion. The Journal of Immunology.200:847-956) 2018 4.8
Mincione Gabriella, Maria C. Di Marcantonio, Chiara Tarantelli, Luca Savino, Donatella Ponti, Marco Marchisio, Paola Lanuti, Silvia Sancilio, Antonella Calogero, Roberta Di Pietro, Raffaella Muraro (2016) Identification of the Zinc Finger 216 (ZNF216) in human carcinoma cells: a potential regulator of EGFR activity. Oncotarget (2016) 7:74947-74965 2016 6,3
First author Donatella Ponti, Daniela Bastianelli, Paolo Rosa, Luca Pacini, Mohsen Ibrahim, Erino Angelo Rendina, Giuseppe Ragona, Antonella Calogero (2015) The transcriptional factor Egr1 promotes B23 expression under stress conditions BMC Cell Biology 16:27. doi: 10.1186/s12860-015-0073-5). 2015 2,34
Camilla Siciliano, Isotta Chimenti, Antonella Bordin, Donatella Ponti, Paola Iudicone, Mariangela Peruzzi, Erino Angelo Rendina, Antonella Calogero, Luca Pierelli , Mohsen Ibrahim, Elena De Falco (2015) The Potential of GMP-Compliant Platelet Lysate to Induce a Permissive State for Cardiovascular Transdifferentiation in Human Mediastinal Adipose Tissue-Derived Mesenchymal Stem Cells BioMed Research International 01/2015.
2015 2,7
Pacini Luca, Bastianelli Daniela, Ponti Donatella, Rosa Paolo, Petrozza Vincenzo, Giannini Giuseppe, Ragona Giuseppe, Calogero Antonella. (2015) Direct correlation between double K-RAS mutation and mucinous carcinoma. Case report. Appl Immunohistochem Mol Morphol 23(2):e4-7. doi: 10.1097/PAI.0000000000000176 2015 2
- Luca Pacini, Elena De Falco, Maria Di Bari, Andrea Coccia, Camilla Siciliano, Donatella Ponti, Antonio Pastore, Vincenzo Petrozza, Antonio Carbone, Ada Tata, Antonella Calogero (2014) M2 muscarinic receptors inhibit cell proliferation and migration in urothelial bladder cancer cells. Cancer Biol Ther. 2014 Aug 22:0. PMID:25482946 2014 3
First author Donatella Ponti, Gian Carlo Bellenchi, Rosa Puca, Daniela Bastianelli, Marella Maroder, Giuseppe Ragona, Pascal Roussel, Marc Thiry, Dan Mercola, Antonella Calogero (2014). The Transcription Factor EGR1 Localizes to the Nucleolus and Is Linked to Suppression of Ribosomal Precursor Synthesis. PLOS ONE, vol. 9, ISSN: 1932-6203, doi: 10.1371/journal.pone.0096037. 2014 3,2
Luca Pacini, Silvia Suffredini, Donatella Ponti, Raffaele Coppini, Giacomo Frati, Giuseppe Ragona, Elisabetta Cerbai, Antonella Calogero (2013). Altered calcium regulation in isolated cardiomyocytes from Egr-1 knock-out mice. Canadian Journal of Physiology and Pharmacology, ISSN: 0008-4212, doi: 10.1139/cjpp-2012-0419. 2012 1,7
Michela Ferretti, Cinzia Fabbiano, Maria Di Bari, Claudia Conte, Emilia Castigli, Miriam Sciaccaluga, Donatella Ponti, Paola Ruggieri, Antonino Raco, Ruggero Ricordy, Antonella Calogero, Ada Maria Tata (2013). M2 receptor activation inhibits cell cycle progression and survival in human glioblastoma cells. Journal of Cellular and Molecular Medicine, vol. 17, p. 552-566, ISSN: 1582-1838, doi: 10.1111/jcmm.12038. 2013 4
Daniele Avitabile, Licia Genovese, Donatella Ponti, D. Ranieri, S. Raffa, Antonella Calogero, Maria R. Torrisi (2013). Nucleolar localization and circadian regulation of Per2S, a novel splicing variant of the Period 2 gene. Cellular and Molecular Life Sciences, ISSN: 1420-9071. 2013 5,8
M. Ferretti, C. Fabbiano, M. Di Bari, D. Ponti, A. Calogero, A.M. Tata (2012). M2 muscarinic receptors inhibit cell proliferation in human glioblastoma cell lines. Life Sciences, ISSN: 0024-3205, doi: 10.1016/j.lfs.2012.04.033. 2012 2,7
Paola Ruggieri, Giorgio Mangino, Bernard Fioretti, Luigi Catacuzzeno, Rosa Puca, Donatella Ponti, Massimo Miscusi, Fabio Franciolini, Giuseppe Ragona, Antonella Calogero (2012). The Inhibition of KCa3.1 Channels Activity Reduces Cell Motility in Glioblastoma Derived Cancer Stem Cells. PLOS ONE, vol. 7, p. 1-12, ISSN: 1932-6203, doi: 10.1371/journal.pone.0047825. 2012 3,2
Calogero A, Porcellini A, Lombari V, Fabbiano C, Arcella A, Miscusi M, Ponti D, Ragona G. (2011). Sensitivity to cisplatin in primary cell lines derived from human glioma correlates with levels of EGR-1 expression. Cancer Cell International, vol. 5, ISSN: 1475-2867, doi: 10.1186/1475-2867-11-5. 2011 2,7
Corresponding author Psaila Rossana, Donatella Ponti, Ponzi Marta, Gigliani Franca, Battaglia Piero Augusto (2010). A small sequence in domain V of the mitochondrial large ribosomal RNA restores Drosophila melanogaster pole cell determination in UV-irradiated embryos. Cellular & Molecular Biology Letters, ISSN: 1425-8153, doi: 10.2478/s11658-010-0013-5. 2010 1,6
First author Donatella Ponti, Maria Troiano, Gian Carlo Bellenchi, Piero Augusto Battaglia, Franca Gigliani (2008) The HIV Tat protein affects processing of ribosomal RNA precursor. BMC Cell Biology 9:32. 2008 2,34
- Piero A. Battaglia; Ponti Donatella; Gigliani Franca (2006) Two phenotypes with a single genotype: the case of butterfly. Caryologia Volume: 59 Issue: 4 Pages: 354-357 2006 0,45
Piero A Battaglia, Donatella Ponti, Valeria Naim, Serenella Venanzi, Rossana Psaila, Franca Gigliani (2005) The HIV-Tat protein induces chromosome number aberrations by affecting mitosis. Cell Motility and the Cytoskeleton 61:129-36. 2005 4,1
First author Donatella Ponti, Maria Luisa Mangoni, Giuseppina Mignogna, Maurizio Simmaco and Donatella Barra (2003) "An amphibian antimicrobial peptide expressed in Nicotiana tabacum confers plant resistance to phytopathogens" Biochemical Journal 370,121-7 2003 5
First author Donatella Ponti, Giuseppina Mignogna, Maria Luisa Mangoni, Daniela De Biase, Maurizio Simmaco and Donatella Barra (1999)” Expression and activity of cyclic and linear analogues of esculentin-1, an antimicrobial peptide from amphibian skin.”European Journal Biochemistry, 263, 921-927 1999 3,16
Rossella Miele, Donatella Ponti, Hans G. Boman, Donatella Barra and Maurizio Simmaco (1998) “A tandem gene coding for bombinins, antibacterial peptides from the frog Bombinina orientalis”. FEBS Lett. 10; 431:23-8 1998 3,6
Ugo Borello, Benedetto Aracri, Claudia Dalmastri, Donatella Farini, Donatella Ponti and Giovanni Giuliano (1993) “Transcriptional Regulation of nuclear genes controlling plastid differentiation in tomato”. Biotechnology Biotechnogical Equipment, 2:51-54 1993 0,38
Giuliano Giuliano, Borello Ugo, Ponti Donatella. (1995) A B-ZIP factor-binding to the the G-Box of light-responsive genes in a phosphorylation-independent fashion. Journal of Cellular Biochemistry Supplement: 21A-504-504 1995 3,12
Klimczak LJ, Farini D, Lin C, Ponti D, Cashmore AR, Giuliano G. (1995) Multiple isoforms of Arabidopsis casein kinase I combine conserved catalytic domains with variable carboxyl-terminal extensions. Plant Physiol;109:687-96.
1995 6

PATENT
Last author Simmaco Maurizio, Barra Donatella, Ponti Donatella. (2001) Transgenic plant with increased resistance against phytopatogens and methods of production. Italian patent no. 2001 RM2001A000268
Last author Barra Donatella, Bossa Francesco, De Biase Daniela, Simmaco Maurizio & Ponti Donatella. (1998) Plasmid for the production of anti-microbial peptides in recombinant bacteria. 1998 RM98A000393

Book

Last author Russell, Peter J. iGenetica: fondamenti / Peter J. Russell; italian edition by Giancarlo Bellenchi, Franca Gigliani, Donatella Ponti Napoli: EdiSES, 2004 [opac SBN] [Monografia] [IT\ICCU\CAG\0762632]
2004

EDITORIAL EXPERIENCE

Role Journal
Associate Editor since 2024 Frontiers in Molecular Biosciences-Molecular Diagnostic and Therapeutics
Guest Editor 2023 Frontiers in Cell and Developmental Biology
Reviewer Biomedicine
Reviewer Histology and Hystopathology
Reviewer Nutrients
Reviewer Perspective Moleuclar Biology
Reviewer Pharmaceutics
Reviewer Cells
Review Cancers
Reviewer Scientific Reports (Nature)
Reviewer
Reviewer
Reviewer Current Issues in Molecular Biology
IScience (Cell)
Cell Oncology

ONG
2024-2027 Title of project
Component of Pharmaceutic POT PI Prof.ssa M. Biava Sapienza University of Rome
School Galilei Sani Latina (5 February and 17-18-20 February 2025).
18.03.2024 Seminar High school “Teodosio Rossi” via Montanno Priverno (Latina) Project Next Generation 3 hours mod. A Sapienza University of Rome
21.12. 2023 Seminar High school “Liceo A. Mancinelli” - via Salvo D’acquisto, 69 (Velletri) Rome
Project Next Generation 3 hours mod.E Sapienza University of Rome
February 2023 Tutor PCTO, PI Prof. Eugenio Lendaro. high school “Istituto Tecnico Galilei” Latina Italy Project: “Fosfatasi alcalina” University of Rome Sapienza, corso della Repubblica 79 Latina.
15-19 April 2024

26-31 March 2025 PI and Tutor PCTO “Recominant DNA” University of Rome Sapienza, Corso della Repubblica 79 Latina. CODICE 112349

PI and Tutor PCTO “Recombinant DNA” University of Rome Sapienza Corso della Repubblica 79 Latina Codice 112349.

PERSONAL SKILL

Molecular Biology: DNA manipulation: expression vector for transient and stabile expression of protein and fusion proteins (tag peptide/GFP/His peptide ex.) Northern and Southern blotting, RT-PCR, Race 5', Race 3'. Screening of cDNA and genomic library, Transcription and Translation in-vitro (rabbit system). RNA and DNA purification. Real Time PCR.
Cell biology Cell lines culture, cell transfection, electroporation, siRNA, immunofluorescence analysis, virus infection. Cell Viability. Cell Proliferation. Experimental model: amphibian; transgenic D. melanogaster; mouse model. Macrophages (BMDM) purification from mouse and cell polarization (M1/M2).
Biochemistry: Electrophoresis of proteins and peptides, protein purification, immunoblotting, immunoprecipitation, ChIP, EMSA. Sucrose and Cs gradient. Cell fractioning and nucleolar purification. Analysis of methylation status of promoter gene. Extraction of nucleolar proteins. Heterologous expression of proteins and peptides. SUnSET. Oligonucleotides synthesis. DNA sequencing. Ribosomes purification.
Microbiology Transformation by Ca/Mg, electroporation, antimicrobial assay. Protein experession

According to law 679/2016 of the Regulation of the European Parliament of 27th April 2016, I hereby express my consent to process and use my data provided in this CV.

2025,04,20.
DONATELLA PONTI, PhD